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Urothelial Carcinoma

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The urothelium is the epithelial lining of renal collecting ducts, calyces, ureters, bladder, and urethra. Urothelial carcinoma (UC), previously referred to as transitional cell carcinoma, is a histopathologic type of cancer that typically arises from the urothelium.

Urological tumours represent approximately 25% of all human cancers. The majority of cases presenting UC are bladder cancers (BC), whereas upper urinary tract urothelial cancer (UTUC) accounts for only 5%–10% of all urothelial malignancies.

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